Ber-EP4

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Ber-EP4 is present on the surface and the cytoplasm of all epithelial cells except the superficial layers of squamous epithelial, hepatocytes and parietal cells. It shows a broad spectrum of reactivity with human epithelial cells including simple epithelia and basal layers of stratified non-keratinized squamous epithelium and epidermis. It does not label mesothelial cells and rarely marks mesotheliomas and has been reported to distinguish between adenocarcinomas from pleural mesotheliomas. Studies also suggest it may be useful for differentiating basal cell carcinoma from other dermatological conditions.

Intended Use

IVD

Source

Mouse Monoclonal

Species Reactivity

Human

Clone

Ber-EP4

Isotype

IgG1

Antigen

Ber-EP4

Localization

Cytoplasm, cell membrane

Positive Control

: Colon and breast cancer

By Letter

B

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1. Ansai S, et al. J Dermatol. 2012 Aug; 39(8):688-92.
2. Saladi RN, et al. Int J Dermatol. 2004 Aug; 43(8):600-3.
3. Koss MN, et al. Ann Diagn Pathol. 1998 Apr; 2(2):93-102.
4. Ordóñez NG. Am J Clin Pathol. 1998 Jan; 109(1):85-9.
5. Jensen ML, Johansen P. Diagn Cytopathol. 1996 Jul; 15(1):33-6.
6. Sheibani K, et al. Am J Surg Pathol. 1991 Aug; 15(8):779-84.
7. Gaffey MJ, et al. Am J Surg Pathol. 1992 Jun; 16(6):593-9.

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