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BCL-6 Mouse Monoclonal Antibody is commonly expressed in diffuse large cell lymphomas, follicular lymphomas and Burkitt’s lymphoma/leukemia. Bcl-6 protein is expressed mainly by follicle center cells, a few interfollicular T lymphocytes and in nodular lymphocyte predominant Hodgkin’s disease. However Blc-6 mouse monoclonal is not expressed in hairy cell leukemia, mantle cell or marginal-zone derived lymphomas. In humans, Bcl-6 encodes for a Kruppel-type zinc finger protein that is believed to be important in germinal center formation. The LN22 clone of Bcl-6 provides superior sensitivity compared to [PIF6].
The Bcl-6 gene, originally cloned from a tumor with 3q27 translocation, is commonly expressed in large cell lymphomas. In humans, Bcl-6 encodes for a Kruppel-type zinc finger protein that is believed to be important in germinal center formation.
AA 1-350 N-terminus human Bcl-6 oncoprotein
Tonsil or Follicular Lymphoma
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