Smoothelin
Smoothelin is a novel cytoskeletal protein that reacts with the 59 kDa and 100 kDa protein, corresponding to Smoothelin A and B, respectively, which are exclusively found in smooth muscle cells (SMC). Cells with SMC-like characteristics, such as myofibroblasts and myoepithelial cells, as well as skeletal and cardiac muscle do not contain Smoothelin. Smoothelin is exclusively expressed in fully differentiated (contractile) smooth muscle cells such as human detrusor and in the human muscularis propria. Studies have also shown Smoothelin as a potential tool in the pathologic staging of invasive urothelial carcinoma, overactive bladder, and in the evaluation of atherosclerotic lesions.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 372 |
A, C |
| Predilute |
PM 372 |
AA |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
