Neuron Specific Enolase Cocktail
NSE recognizes a protein of 46kDa, identified as neuron-specific enolase (NSE). Enolases are homo- or heterodimers of the three subunits: alpha (46kDa), beta (44kDa), and gamma (46kDa). The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE shows no cross-reaction with the alpha- or beta-subunits of NSE. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms. Biocare’’s DT01 + BC100 antibody cocktail is excellent for immunohistochemical staining of formalin-fixed, paraffin-embedded tissues.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 049 |
A, B, C |
| Predilute |
PM 049 |
AA |
| intelliPATH™ |
IP 049 |
G10 |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
