CD117/c-kit
CD117/c-kit) is a member of Tyrosine Kinase kDa(-3) Receptor (TKR) family and highly homologous to receptor PDGF and CSF-1. This antibody recognizes the extracellular domain and is expressed by a variety of normal and abnormal cell types.
In normal cells, the CD117 antibody has been shown to label breast epithelium, germ cells, melanocytes, stem cells and mast cells. In abnormal cells, it has been shown to label testicular germ cells, endometrial carcinomas, papillary and follicular thyroid carcinomas, small cell carcinomas, melanomas and ovarian epithelial carcinomas. It has also been shown to be an effective marker for mast cell disorders, gastrointestinal stromal tumors and immunotyping of blasts in human bone marrow.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CME 296 |
AK, BK, CK |
| Predilute |
PME 296 |
AA |
| intelliPATH™ |
IP 296 |
G10 |
| VP Echelon |
Use Predilute |
|
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
