Cytokeratin 7
Cytokeratin 7 is an intermediate filament protein (IFP) of 54kDa that recognizes the simple epithelium found in most glandular and transitional epithelia; but not that which is found in the stratified squamous epithelia. This monoclonal antibody [clone OV-TL 12/30] is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, and is expressed in epithelial cells of ovary, lung, and breast, but not of colon or gastrointestinal tract. It is often used in conjunction with cytokeratin 20 in distinguishing ovarian, pulmonary, and breast carcinomas (CK7+) from colon carcinomas (CK7-).
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 061 |
A, B, C |
| Predilute |
PM 061 |
AA |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
Use Predilute |
|
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
