HMB45

Melanoma stained with HMB45 antibody

HMB45 reacts with a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. The HMB45-reactive antigen is present in cutaneous melanocytes, prenatal and infantile retinal pigment epithelium (RPE), and melanoma cells and is thought to be oncofetal in nature. This antibody has been shown to label the majority of melanomas.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control
Ordering Information Catalog Number Volume
Concentrate CM 057 A, B, C
Predilute PM 057 AA
intelliPATH™ IP 057 G10
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml