CD30
The Ki-1 antigen, recognizes a single chain transmembrane glycoprotein that has been demonstrated to be homologous to members of the nerve growth factor receptor superfamily. The mature 120 kDa molecule is formed from 90 kDa precursor molecule processed in the Golgi system. The Ki-1 (CD30) antigen is expressed in mononuclear Hodgkin’s and multinucleated Reed-Sternberg cells in Hodgkin’s disease. It is expressed by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells. CD30 is also expressed in embryonal carcinomas. It distinguishes large cell lymphomas derived from activated lymphoid cells, from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells, or from anaplastic carcinomas. CD30 and CD15 primary antibodies may be used in tandem to differentiate between anaplastic large cell lymphoma and Hodgkin’s disease (Reed-Sternberg cells).
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 346 |
A, B, C |
| Predilute |
PM 346 |
AA |
| intelliPATH™ |
IP 346 |
G10 |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
