CD44
CD44 antigen is a transmembranous glycoprotein (80 kDa) antibody that is specific for epitope 3 of the CD44 H molecule. CD44 (HCAM) is a cell adhesion molecule that plays an important role in the cascade of metastasis and progression of human malignant tumours. CD44 antigen is present on T lymphocytes, granulocytes, red blood cells, brain and epithelial cells. The standard isoform, CD44s, are also expressed in a wide range of normal tissues such as tonsil, skin, bladder and cervical squamous epithelium. In breast cancer studies, CD44 expression, as assessed by immunohistochemical staining demonstrated a favorable prognostic factor in patients with node-negative invasive breast carcinoma. Further studies have shown a subpopulation of CD44+/CD24- in breast cancer cells have stem/progenitor cell properties.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 318 |
A, C |
| Predilute |
PM 318 |
AA |
| intelliPATH™ |
IP 318 |
G10 |
| VP Echelon |
Use Predilute |
|
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
