Villin

Colon cancer stained with Villin antibody.

Villin is a cytoskeletal protein of microvilli of epithelial cell brush border found in absorptive cells of the intestine and proximal renal tubes. Villin is a very specific marker for gastrointestinal tumors and adenocarcinomas of the pancreas. Other subsets of tumors stained with Villin are Merkel cell, lung (with rootlets), ovarian and kidney. It does not stain breast cancer. Used in a panel with CK7, CK20/CDX-2 and TTF-1, Villin can be very useful in differentiating colon adenocarcinoma from breast carcinoma and from lung adenocarcinoma.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization ,
Positive Control
Normal Tissue ,
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate CM 094 A, B, C
Predilute PM 094 AA
intelliPATH™ N/A N/A
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml
Data Sheets
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