Villin
Villin is a cytoskeletal protein of microvilli of epithelial cell brush border found in absorptive cells of the intestine and proximal renal tubes. Villin is a very specific marker for gastrointestinal tumors and adenocarcinomas of the pancreas. Other subsets of tumors stained with Villin are Merkel cell, lung (with rootlets), ovarian and kidney. It does not stain breast cancer. Used in a panel with CK7, CK20/CDX-2 and TTF-1, Villin can be very useful in differentiating colon adenocarcinoma from breast carcinoma and from lung adenocarcinoma.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 094 |
A, B, C |
| Predilute |
PM 094 |
AA |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |