TRIM29
Tripartite motif-containing 29 (TRIM29), also known as ataxia-telangiectasia group D complementing gene (ATDC) belongs to the TRIM protein family which has unique structural characteristics. A high expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. In-house studies showed that TRIM29 was able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with a 92% positive accuracy, if used in a panel with antibodies such as TTF-1, p63, CK5/6, Napsin-A etc. Studies have also shown that TRIM29 expression is strongly associated with histological grade, tumor size, extent of invasion, and poorer survival rates.
*Part of the PulmoPanel™ Kit for diagnosing lung cancer, to order use Cat. No. PPM 435 AAK.
The PulmoPanel™ Kit includes: CK5, Desmoglein 3, Napsin A, p63, TRIM29 and TTF-1.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
N/A |
N/A |
| Predilute |
PP 416 |
AA |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
