Smooth Muscle Actin

Prostate stained with SMA antibody

This antibody recognizes the alpha-smooth muscle isoform of actin. It shows no crossreaction with actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial). A synthetic peptide corresponding to N-terminus of human Alpha-actin was used as immunogen. Smooth Muscle Actin stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary glands are also stained as they also contain actin. This MAb is reportedly useful for identifying tumors arising from smooth muscle and myoepithelial cells.

Specifications  
Intended Use
Source
Species Reactivity , ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control , ,
Normal Tissue , ,
Abnormal Tissue ,
Ordering Information Catalog Number Volume
Concentrate CME 305 A, B
Predilute PME 305 AA
intelliPATH™ N/A N/A
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml
Data Sheets
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