Epstein-Barr Virus

Hodgkins lymphoma stained with EBV antibody cocktail

This antibody reacts with a 60 kD latent membrane protein encoded by the BNLF1 gene of the Epstein Barr Virus (EBV). All three antibodies in this cocktail recognize distinct epitopes in the hydrophillic carboxyl region of the latent membrane protein (LMP). EBV has been implicated with Hodgkin’s disease, and may be involved in the pathogenesis of Hodgkin’s occurring in children. Other studies have shown a low incidence of EBV in B-cell type lymphomas unless patients were immunologically impaired, such as post-organ transplantation or autoimmune type diseases. This antibody does stain EBV + Burkitt’s lymphomas and has shown some crossreactivity with smooth muscle and blood vessels.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone ,
Isotype
Antigen
Cellular Localization ,
Positive Control
Normal Tissue
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate N/A N/A
Predilute PM 111 AA
intelliPATH™ N/A N/A
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml
Data Sheets
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