CDX2

Colon cancer stained with CDX2 antibody

CDX2 is a homeobox gene that encodes an intestine-specific transcription factor. It is expressed in the nuclei of epithelial cells of the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas. It has also been identified in intestinal metaplasia of the stomach and in intestinal-type gastric cancer. CDX2 is not expressed in normal gastric mucosa. Studies have shown that the CDX2 marker is superior to CK20.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control
Normal Tissue
Abnormal Tissue , ,
Ordering Information Catalog Number Volume
Concentrate CM 226 A, B, C
Predilute PM 226 AA, H
intelliPATH™ IP 226 G10, G20
VP Echelon VP 226 G
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml