CA 125

Ovarian cancer stained with CA 125 antibody

CA125 recognizes an epitope on a molecule called Cancer Antigen 125 (CA125). Studies have show that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are negative.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control ,
Normal Tissue
Abnormal Tissue ,
Ordering Information Catalog Number Volume
Concentrate CM 101 AK, CK
Predilute PM 101 AA
intelliPATH™ IP 101 G10
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml