Ber-EP4

Breast cancer stained with Ber-EP4 antibody

Ber-EP4 recognizes two glycoproteins of 34 and 49 kDa present on the surface and the cytoplasm of all epithelial cells except the superficial layers of squamous epithelial, hepatocytes and parietal cells. It does not label mesothelial cells and rarely marks mesotheliomas. It shows a broad spectrum of reactivity with human epithelial cells including simple epithelia and basal layers of stratified non-keratinized squamous epithelium and epidermis. Other similar antibodies include: AUA1, ESA [VU-1D9] and MOC-31. Ber-EP4 reportedly distinguishes between adenocarcinomas from pleural mesotheliomas.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control ,
Normal Tissue
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate N/A N/A
Predilute PM 107 AA
intelliPATH™ IP 107 G10
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml