L26 (CD20) reacts with a 30-33 kDa polypeptide present in B-cells. L26 reacts with the majority of B-cells present in peripheral blood and lymphoid tissues. In normal lymphoid tissue, L26 marks B-cells in germinal centers, particularly immunoblasts. This antibody has been shown to be a reliable pan B-cell marker. It rarely marks Tcells.
This rabbit monoclonal CD3 reacts with the intracytoplasmic portion of the CD3 antigen expressed by T-cells. It stains human T-cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues.
L26 and CD3 have been cocktailed to be used with Biocare’s MACH 2 Double Stain 1. L26 is stained with Fast Red and CD3 is stained with DAB
| Specifications | |
|---|---|
| Intended Use | IVD |
| Source | Mouse Monoclonal, Rabbit Monoclonal |
| Species Reactivity | Human, Others not tested |
| Clone | L26 + SP7 |
| Isotype | IgG2a + Rabbit IgG |
| Antigen | B-cells, T-Cells |
| Cellular Localization | Cytoplasmic |
| Positive Control | Tonsil |
| Normal Tissue | Tonsil |
| Abnormal Tissue | B-cell lymphoma, T-cell lymphoma |
| Ordering Information | Catalog Number | Volume |
|---|---|---|
| Concentrate | N/A | N/A |
| Predilute | PM 237DS | AA |
| intelliPATH™ | N/A | N/A |
| VP Echelon | N/A | N/A |
| A / AK = 0.1 ml | B / BK = 0.5 ml | C / CK = 1.0 ml | G5 = 5.0 ml | AA = 6.0 ml | H / G25 = 25 ml | L = 100 ml |
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| Data Sheets |
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