| ANTIBODY PHOTO | ADH-5 (Breast Marker Cocktail) | |
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ADH-5 (Breast Marker Cocktail) Description ADH-5 Breast Marker Cocktail (Atypical Ductal Hyperplasia) is composed of CK5+CK14+p63+CK7+CK18 antibodies. This cocktail can be used in a wide range of applications for breast cancer. Invasive versus noninvasive breast lesions can be easily distinguished with the presence or absence of myoepithelium (CK5/14 and/or p63) (DAB) and glandular staining of breast cancer with CK7/18 (Fast Red). This 5 antibody cocktail in one single application can also distinguish hyperplasia of the usual type versus atypical hyperplasia, and distinguish micro invasive and basal phenotypes in most breast cancers. Luminal or cytoplasmic staining may also be observed in CK5/14 and/or CK7/18 staining (bimodal). In certain cases, only CK5/14 luminal staining is observed representing a basal-phenotype classification. Breast cancer with bimodal and/or basal-like staining are associated with poor prognosis. |
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| PHOTO DESC. | Cat No. | |
| Hyperplasia of the usual type; p63 staining myoeplithelia, CK5 /14 and CKCK7/18, luminal. | intelliPATH FLX | IP 360DS G10 |
| CONCENTRATE | N/A | |
| PREDILUTE | PM 360DS AA, H | |
| CLONE | XM26, LL002, BC4A4, BC1 and E431-1 | |
| DOWNLOADS | SOURCE | Mouse and Rabbit Monoclonal |
| ISOTYPE | IgG1/kappa, IgG3, IgG2a/kappa, Rabbit IgG and Rabbit IgG | |
| ANTIGEN | CK5/14 + p63 + CK7 + CK18 | |
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