| ANTIBODY PHOTO | c-erbB-2/HER2 Rabbit Monoclonal | |
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c-erbB-2/HER2 Rabbit Monoclonal Description This antibody recognizes a protein of 185 kDa, identified as the second member (cerbB2/HER-2) of the c-erbB family. This monoclonal antibody is directed against the cytoplasmic domain of the human c-erbB-2 protein. The c-erbB-2 protein is closely related in structure to the epidermal growth factor receptor. The c-erb-B2 protein is overexpressed in a variety of carcinomas, especially those of breast and ovary. Immunohistochemical staining correlates with gene amplification. Studies have shown that c-erbB-2 positive breast cancer usually correlates with negative staining for estrogen and progesterone receptors; thus a poorer predictive outcome is correlated with c-erbB-2 staining. |
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| PHOTO DESC. | Cat No. | |
| Breast cancer stained with c-erbB-2 rabbit monoclonal antibody. | intelliPATH FLX | IP 342 G10 |
| CONCENTRATE | CME 342 A, B | |
| PREDILUTE | PME 342 AA | |
| CLONE | EP1045Y | |
| DOWNLOADS | SOURCE | Rabbit Monoclonal |
| ISOTYPE | Rabbit IgG | |
| ANTIGEN | c-erbB-2 protein | |
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