| ANTIBODY PHOTO | CD24 | |
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CD24 Description CD24 (30-70kDa) is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein. It is a mucin-like adhesion molecule. CD24 functionally enhances the metastatic potential of malignant cells, as it has also been identified as a ligand of P-selection, an adhesion receptor on activated endothelial cells and platelets. Research has shown CD24 expression as a potentially significant parameter for a wide variety of human cancer diagnosis and for patient prognosis. Elevated CD24 membranous expression and, in particular, cytoplasmic staining seem to predict malignant transformation. Recent studies have shown CD24 as a prognostic marker for breast cancer and more specifically for tamoxifen-resistant breast cancer cases. Further studies have shown a subpopulation (CD44+ / CD24-) of breast cancer cells reported to have stem/progenitor cell properties. |
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| PHOTO DESC. | Cat No. | |
| Breast cancer stained with CD24 antibody. | intelliPATH FLX | N/A |
| CONCENTRATE | CM 323 A, B, C | |
| PREDILUTE | N/A | |
| CLONE | SN3b | |
| DOWNLOADS | SOURCE | Mouse monoclonal |
| ISOTYPE | IgM/kappa | |
| ANTIGEN | CD24 | |
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