Retinoblastoma
1F8 recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. The epitope is localized between aa703-772 of human Rb protein. It shows no cross-reaction with p107 or p300. The retinoblastoma gene product has been shown to play a key role in cell cycle control and is known as a tumor suppressor gene. Loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including mammary carcinoma, esophageal cancer, squamous cell carcinoma and cervical cancer.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 211 |
A |
| Predilute |
N/A |
N/A |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
