Androgen Receptor
The androgen receptor antibody recognizes the protein of 110kDa molecular weight. It reacts with full length and A form of the receptor. It is highly specific and does not cross-react with estrogen, progesterone and glucocorticoid receptors. The expression of AR is reportedly inversely correlated with poorly differentiated tumors (well differentiated tumors show high expression of AR and poorly-differentiated tumors show low or no expression of androgen receptor). In prostate cancer, androgen has been proposed as a marker of hormone-responsiveness similar to estrogen receptor and breast cancer, thus high expression of androgen receptor in prostate cancer biopsies may help identify patients that would respond anti-androgen therapy. Other applications for androgen receptor include breast cancer, Paget’s disease and dermatopathology.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 109 |
A |
| Predilute |
PM 109 |
AA |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
